Head Fixation Station for Mice

The Head Fixation Station for Mice is designed for stable and repeatable head-fixed experiments in preclinical neuroscience research. It provides a compact and reliable platform for studies that require precise animal positioning, including functional ultrasound imaging, two-photon imaging, optogenetics, electrophysiology, behavioral training, and multimodal neuroimaging workflows.

This station is commonly used when performing functional ultrasound imaging (fUS) or two-photon imaging in mice, where stable head positioning is essential for acquiring high-quality neural or vascular signals. The system helps reduce motion artifacts while allowing researchers to maintain consistent positioning across repeated experimental sessions.

Built with a rigid base and adjustable fixation components, the station supports accurate alignment of the mouse head relative to the imaging probe, microscope objective, or other experimental devices. Its modular structure makes it suitable for integration with treadmills, behavioral platforms, stereotaxic accessories, and custom laboratory setups.

Key Features

• Designed for mouse head-fixed neuroscience experiments
• Suitable for fUS, two-photon imaging, optogenetics, and electrophysiology workflows
• Stable fixation structure helps reduce motion artifacts during imaging
• Adjustable components support consistent positioning and alignment
• Compatible with repeated training and longitudinal experimental sessions
• Compact footprint for easy integration with imaging rigs and behavioral platforms
• Durable, easy-to-clean construction for routine laboratory use

Applications

• Functional ultrasound imaging in mice
• Two-photon calcium imaging and vascular imaging
• Head-fixed behavioral experiments
• Mouse treadmill or running-wheel experiments
• Multimodal neuroscience research
• Longitudinal imaging and repeated-measure studies
• Motor, sensory, cognitive, and disease-model research